Pipeline – Aurora

About Aurora Kinases

Aurora kinases A and B are required for cells to both enter and proceed through mitosis, which is the process by which copies of the duplicated DNA chromosomes are segregated into two daughter cells. Moreover, Aurora kinases are over-expressed in a variety of cancers including pancreatic, ovarian, colon, breast, liver, lung, thyroid and bladder cancer. These cellular proteins therefore represent attractive targets for treating a wide range of cancers.

More information about this programme is avaialble here: Aurora (download pdf)